Mast Cell Changes in Two Different Treatment Groups of A Sheep Model of Pulmonary Fibrosis

Bijani R*, Nimanthi VDS, Or

Abstract

Idiopathic Pulmonary fibrosis (IPF) is a progressive and devastating disease. This chronic disease is characterised by the accumulation of Extracellular Matrix (ECM) and remodeling of the lung tissue. The pathogenesis of the IPF is unclear, however, there are a certain number of known environmental and genetic risk factors that have been linked to the development of the condition such as smoking and aging.