Research Article
Ranjan Kumar Giri a, Sunil Kum
Abstract
Lipid lowering effect of the hydro-alcoholic extract of the flower of Tecoma stans L. was evaluated in triton and diet induced hyperlipidemic models of wistar albino rats. The extract at 125 and 250mg/kg dose levels inhibited the elevation in serum cholesterol and triglyceride levels on Triton WR 1339 administration rats. The extract at the same dose level significantly attenuated the elevated serum total cholesterol and triglycerides with an increase in high-density lipoprotein cholesterol in high-fat diet-induced hyperlipidemic rats. The standard dose atrovastatin in the former and gemfibrozil in the later studies showed slightly better effects. The outcome of the study revels the lipid lowering activity of hydro-alcoholic extract of Tecoma stans L. flowers in dyslipidaemic conditions by interfering with the biosynthesis of cholesterol and utilization of lipids.