Isolation and Characterisation of clerodane diterpenoids from the traditional medicinal plant -Tinospora glabra (Burm. f.) Merrill.

Rathnasamy Rishikesan, Ravikum

Abstract

Four clerodane diterpenoids , namely, tinosporide, 8-hydroxy tinosporide, columbin and columbin acetate have been isolated from the chloroform extract of the aerial parts of the traditional medicinal plant Tinospora glabra. furthertinosporide was acylated to form acetyl and diacetyltinosporide. The structures of the compounds were characterized by using Mass, Proton and 13C-NMR respectively.