Is there a Relationship between Helicobacter Pylori Infection and Esophageal Cancer?

Berhe Dessalegn Tuamay

Abstract

Background: Several studies had shown that Helicobacter pylori infection is inversely associated with esophageal cancer. These studies had claimed that infection had associated with protective effect. However, other studies come out with different conclusion about the relationship, as a result, the issue has remained controversial. Objective: The aim of this systematic review and meta-analysis was to examine the association between Helicobacter pylori infection and esophageal cancer. Esophageal cancer is among the foremost frequent neoplasms, a main reason for cancer-related deaths worldwide and a clinically difficult sickness requiring a multidisciplinary approach [15]. muscular structure cancer is split into 2 microscopic anatomy types: muscular structure epithelial cell malignant neoplastic disease (ESCC), associated principally with environmental risk factors (e.g., smoking and alcohol consumption), and muscular structure glandular carcinoma (EAC) situated on the point of the viscus junction, etiologically not to mention esophageal reflux sickness (GERD). within the westernized population, the incidence of EAC redoubled sharply, displacing ESCC, the latter accounting for many of the incidence of muscular structure cancer fifty years past.