Importance of assessing total vitamin B12 and active B12 levels in cancer patients

Hemant J. Vira

Abstract

Cancer patients are immunocompromised due to the disease itself and also due to the weakness that ensue. The importance of measurements of Vitamin B12 levels has been increasingly implicated of which the measurements of active vitamin B12 have been given more importance. It also serves as an important coenzyme in various cellular processes such as regenerating methionine for protein synthesis, DNA synthesis, and DNA methylation.

Relevant Publications in Journal of Molecular Cancer