Identification Of Mycobacterium Tuberculosis Gene Mutation That Caused Rifampicin Resistance In Mdr Tb Patients In H. Adam Malik Medan, North Sumatera, Indonesia

Rahmat Aditya

Abstract

TB is an infectious disease that ranks second in death (1.5 million cases) in the world. Indonesia is currently a country with a high burden of drug resistant TB in the world, especially MDR-TB. This study aims to determine mutations in the gene that M. tuberculosis cause resistance to rifampicin in the Haji Adam Malik General Hospital, Medan, determine which codons are mutated in the rpoB gene.