Research Article
Ma. Klarisse M. Dioso, Diane C
Abstract
Synsepalumdulcificum (Schumach. & Thonn.) Daniell(Sapotaceae), also known as miracle berry because of its ability to make sour foods taste sweet was the focus of the present study. The hypoglycemic effects of its fruit and leaf extracts on the blood glucose level of alloxan-induced diabetic albino rats were determined and compared with the positive control using metformin. Twenty-five albino rats were induced with type 2 diabetes mellitus usin galloxan and were grouped and treated into five treatments (positive control using metformin, 50% fruit extract, 50% leaf extract, 100% fruit extract, 100% leaf extract).Blood glucose level were analyzed and compared. Results revealed that the two concentrations, i.e. 50% and 100%, of both fruit and leaf extracts induce the same significant lowering effects on the blood glucose level of the test rats. This may be due to the natural compound miraculin in the fruit and phytochemicals, such as flavonoids and saponins in its leaves.