Original Articles
I Amar Sandeep, PT Sankeerth ,
Abstract
The present study was aimed to formulate and evaluate fast dissolving oral films of Zolmitriptan using propylene glycol, HPMC-E50 LV and sodium starch glycolate. The suitable plasticizer and its concentration were selected based on flexibility, tensile strength and stickiness of the film. The films are prepared by solvent casting method and characterized by UV, FTIR studies. The films were evaluated for SEM, disintegration time, Folding endurance, Tensile Strength, Mouth dissolving time, Thickness, content uniformity and in vitro dissolution studies.