Fluorescence and anti-TB study of chiral schiff bases of (1R, 2R)-(+)-1,2- diphenylethane-1,2-diamine and their transition metal complexes

Udaysinha C. Patil, Mustapha M

Abstract

Transition metal complexes with Schiff bases derived from (1R,2R)-(+)-1,2-diphenylethylene-1,2-diamine and 5-Rsalicylaldehyde (R= H, Br, Cl) have been synthesized and characterized by NMR, MASS, IR and UV-visible Spectroscopies. The fluorescence spectra of the chiral ligands and their related complexes have also been measured. The absorption spectra of the metal complexes in the visible region are consistent with near square planar coordination geometries. Trends in absorption spectra over the series of complexes can be correlated with electronic effects of the substituents at position 5 of the salicylaldehyde. Schiff base ligands and their metal complexes have been screened for anti-tuberculosis activity.