Research Article
Thelma J and Asha Devi NK
Abstract
Evaluation of Probiotics from Mucus Associated Epibiotic Bacteria on Marine Fishes Probiotics are live microbial food supplements that benefit the health of the consumers by maintaining or improving the host intestinal micro biome. The advantage of probiotics is that they are non pathogenic and persistent in the GI tract. Plenty of evidence exists on the positive effects of probiotics on human health. Earlier works revealed that probiotics substantially reduce the pathogenic bacterial strains in the intestine. Further, probiotics possess immunomodulatory, antimutagenic and antagonistic properties. Probiotics represents an effective alternative to the use of synthetic substances in nutrition in medicine. Though selection of suitable probiotics bacteria is the principle basis for enhancing the commercial application of the compound concerned, improving the bio-therapeutic action and functional properties of probiotic product requires proper screening and structural elucidation so that it permits rational approaches in the effective exploitation of probiotic biomedical applications. The present study is intended to isolate and screen marine bacteria for its probiotics potential. Marine bacteria is chosen for this study because they are often under extreme conditions like pressure, temperature, salinity and depletion of micronutrients, which leads to the synthesis of certain biologically active compounds that enhance its survival. Deciphering the chemical structure of the probiotics compound will facilitate to unravel novel scaffolds with diverse pharmacological properties. Therefore, this study is intended to evaluate probiotics from mucus associated epibiotic bacteria on marine fishes and to unravel the chemical structure for their potential therapeutic application.