Research Article
Rishi Kumara, Parveen Kumar Go
Abstract
The present manuscript was mainly focused to evaluate the multiherbal formulation PACT (containing extracts of Pongamia pinnata Linn., Artocarpus lakoocha, Cynodon dactylon Pers. and Tridax procumbens Linn.) for wound healing potential employing two common wound models i.e. excision wound and incision wound models. The wound contraction area and epithelialization period was measured in excision model while wound breaking strength and hydroxyproline contents were measured in incision wound model. The PACT significantly increased wound contraction, epithelialization, wound breaking strength and hydroxyproline contents when compared with control and the results were further supported by histopathological studies. This study concluded that this formulation exhibit potent wound healing efficacy in preclinical experiments and can further be studied for clinical purposes.