Evaluation of 4-Hydroxy-Coumarin Derivatives as Antimicrobial Agents

Kailash Pancholi, Mahendra Bor

Abstract

Synthesis of a series of 4-hydroxy-6-methyl-3-(substituted methyl)-2H-chromen-2-one (4h-m) was achieved from different secondary amine, Formaldehyde and 4-Hydroxy-6-methyl-2H-chromen-2-one using Con. HCl added refluxed within 8 hrs with good yield. The structures of the products were supported by FTIR, PMR and Mass Spectra data.