Efficient, one-pot synthesis of
-aminonitriles via Strecker reaction: New recyclable catalysts

Mahmood Kamali

Abstract

Pyridine dicarboxylic acid guanidine–cobalt complex ((GH)2[Co(H2O)6][Co(pydc)2]2) and uranyl acetate (UO2(CH3COO)2·2H2O) catalyze one-pot, three-component coupling of aldehydes, amines, and potassium cyanide to afford the corresponding
-aminonitriles. The significant features of this method are simple work-up procedure, shorter reaction times and excellent product yields. Also, these two catalysts were recyclable for four consecutive runs.