Effects of Moringa oleifera Leaves Extract on Haematological Parameters of Phenylhydrazine Anaemia Induced Wistar Rats

Anslem O Ajugwo, Philippe E

Abstract

Moringa oleifera is known for its therapeutic effects as it has been long used in treatment of many diseases. The haematinic effect of this plant was investigated in this work. The work was carried in Madonna University Elele Campus Rivers State. A total of 15 rats were procured and grouped into three groups and allowed to acclimatize for one week. Phenyl hydrazine was used to induce the anaemia in all the groups; the extract was prepared and administered orally using oral gavage. The rats were grouped into three groups. Group A served as control while groups B and C served as test group and were administered with 200 mg per body weight of Moringa oleifera leaf extract and 300 mg per body weight of same extract respectively. Blood samples were collected through ocular puncture after 28 days and analysed for haematological parameters using standard manual methods. Results showed that there was significant (P<0.05) increase in red blood cell count, hemoglobin count, packed cell volume and white blood cell count. Oral administration of Moringa oleifera leaf extract irrespective of the dose has the tendency to increase blood parameters such as WBC, RBC, Hb and PCV in anaemic rats.

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