Original Articles
Jyoti S. Patil, Akram A. Naika
Abstract
Brewer's yeast may have beneficial effects on insulin receptors in diabetic rats because of its glucose tolerance factor. This study was conducted to investigate the effects of Brewer's yeast on glycemia and lipid profile in Streptozotocin (STZ) induced diabetic rats. Twenty four Wistar albino rats of either sex weighing 170 - 220 g bw were divided into four groups, (i) Control (ii) Control treated with Brewer’s yeast iii) STZ (60 mg/kg body wt) induced diabetic rats iv) STZ induced diabetic rats treated with Brewer’s yeast. Effect of a four-week oral administration of Brewer’s yeast (160 mg/kg/day) on the glucose homeostasis (RBS & HbA1c) & lipid profile was assessed in Control & STZ -induced diabetic rats. Body weight, food consumption, blood glucose, lipid profile were measured. Administration of STZ produced a significant increase in blood glucose and HbA1c levels (p