Eco-friendly water as a solvent for the one-pot synthesis of 2-aminothiazoles

C. Rajendiran, P. Nagarajan an

Abstract

An efficient one-pot environmentally benign greener synthetic method for the preparation of 2-amino thiazole derivatives from aldehydes, ketones and b-keto esters using aqueous hydrobromic acid and hydrogen peroxide as bromine source in water solvent.