Dual release tablet: Clinical outcome and evaluation

C. Rubina Reichal*1, N. Thirum

Abstract

The goal in designing the bilayer tablets are suitable for the sequential release of two drugs in which one layer is immediate release as loading dose and second layer as maintenance dose. The Fixed Dose Combination (FDC) of two or more drugs in single dosage form, which is more safe and effective for single or different diseases. The bimodal release of formulation is mainly used to achieve rapid and extended release in a single dosage form. For good quality bilayer tablet, the machinery should be constructed as per GMP. The present study focuses the dual release tablets on different types of press, technology and the therapeutic benefits of bilayer tablets.

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