Device Closure of Large Patent Ductus Arteriosus (PDA) in Young Infants: Analysis of Cases In a Bangladeshi Centre.

Nurun Nahar Fatema

Abstract

The incidence of isolated PDA has been estimated at 1:2000 to 1:5000 births which is about10 to 12 percent of all congenital heart disease1.Surgical closure of PDA was long been established but number reduced significantly as even neonatal large tubular PDAs are being closed by transcatheter technique safely and efficiently2 .Transcatheter closure of PDA using coil or device is an established method for older children and adults3. Since the first experience by Porstmann et al in 19674, technical improvement in device design and delivery system led to a revolutionary change in the field of intervention. Device closure in infants are challenging because most of them are symptomatic, failed to thrive (FTT) and body weight is less, need to close PDA for very large size which led tosevere pulmonary hypertension or heart failure. Sofavorable size device, hardware, avoidance of complications like mechanical obstruction to aorta or left pulmonary artery is a concern as these vessels are small size in comparison to the device size5,6. This study was conducted with an aim to see the outcome of transcatheter closure of PDA in infants upto one year of age with follow upto 4 months to 5 years.

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