Development of Technology and Studying of Syrup with Acorus Calamus Rhizome Extract

LA Karpenko, V.H. Demianenko,

Abstract

This article includes the description of obtaining of Acorus Calamus rhizome extract by the percolation method and the formulation of this extract in the syrup as a pharmaceutical dosage form. The percolation rate was 0.8 ml/min. The extraction of raw materials fraction with a particles size 0.25-3 mm has been investigated. It was found that the using of 50% ethanol as the extractant maximizes raw material exhaustion at a ratio of raw material: extractant 1 : 6. The results of the syrup development with the Acorus Calamus extract have been shown that the optimal base was sugar syrup. Such physical-chemical data as description, density, identification of the syrup have been determined