Original Articles
B. A. Patel, S. J. P , Parmar1
Abstract
A simple, accurate, and precise HPTLC method has been developed and validated for the estimation of Carvedilol Phosphate (CP) from bulk drug and tablet formulations. silica gel 60 GF 254 as the stationary phase. The solvent s v/v/v). This system was found to give integration was performed at a wavelength of 243nm. concentration range of 100ng/spot to 200ng/spot relationship with r2 = 0.990. The method was validated method was successfully applied for determination of drug in tablets, wherein no interference from tablets excipients was observed, indicating the specificity of the developed method. Thus, the proposed method can be used successfully for routine analysis of Carvedilol Phosphate from bulk and formulation.