Determination of floating ability of Ocimum tenuiflorum Linn seed mucilage isolated by defatting method

Meghana S. Kamble *, Satish D.

Abstract

The aim of present study was to determine the floating ability of seed mucilage of Ocimum Tenuiflorum Linn. The mucilage was isolated by defatting method. Four tablet formulations of model drug diltiazem HCl were prepared using Ocimum Tenuiflorum Linn seed mucilage in varying concentrations of floating agent. The formulations were evaluated for buoyancy lag time but tablets did not float. The Ocimum Tenuiflorum Linn seed mucilage used alone as a floating agent failed to show floating ability. However it may show floating property if combined with other floating polymers.