Detection of antimicrobial and antimycotic activities of African garden egg fruits (S.melongena L.) against pathogenic organisms in solvents of varying polarities

Research Article

George Daye Mandy C., Waribo H

Abstract

The present study was carried out to investigate the antibacterial and antifungal activity of garden egg plant (Solanum Melongena L). Acetone, Methanol and distilled water extracts of the plant was tested against antibiotic resistant bacteria (Staphylococcus Spp, Eschericha coli, and Proteus spp.) and fungus (Candida Spp). The result obtained revealed antibacterial effect of acetone and methanol extract on Escherichia coli and proteus Spp at 20- 40g and 80g respectively but was not effective with water as extractant, as a result of these solvents ability to solubilize the active agent in garden egg unlike water. This means garden egg extract can be utilized as Nigerian genetic resource to obtain cheap antimicrobial drugs in addition to their nutritional value. However, no extract revealed any antimycotic effect on candida spp, meaning the extracts cannot substitute any of the existing antifungal drugs.

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