Coumarins from the stem bark of Feronia limonia

Tjitjik Srie Tjahjandarie

Abstract

Three coumarins were isolated from the stem bark of Feronia limonia namely as auraptene (1), osthol (2), and xhantotoxin (3). Their structures were elucidated by spectroscopic methods including UV, IR, HRESIMS, 1D and 2D NMR analysis. Compounds 1–3 were evaluated for their cytotoxic properties against HeLa cells, showing their IC50 were 65.09, 7.62, and 21.51 ppm, respectively.

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