Original Articles
Nimesh Patel, Maulik M. Patel
Abstract
As the practice of paediatric day care surgery advances, the search continues for anaesthetic agent that provides rapid smooth induction, stable patients’ hemodynamics, quick emergence and least side effects. Sevoflurane and propofol both are having cardiovascular and respiratory stable profile in pediatric anaesthesia. to compare the cardiovascular and respiratory changes during induction, maintenance and recovery with propofol and sevoflurane anaesthesia in paediatric day surgery. In this randomized study, a total of fifty children, American Society of Anaesthesiologist (ASA) status I or II, were assigned randomly to intravenous (i.v.) propofol or inhalatory sevoflurane group. N2O was used in both groups. Heart rate, Mean blood pressure (MBP) and peripheral oxygen saturation (SpO2 ) were observed and noted during induction, maintenance and recovery. Student t test was used to determine statistical significance of hemodynamic data. No significant differences were detected in age, sex, weight and ASA grading in both the groups performed. The changes in heart rate were comparable. The mean blood pressure was significantly lower in propofol group as compared to sevoflurane group at various intervals (p value<0.05). The changes in mean SpO2 were comparable except immediately after induction. Sevoflurane showed better intraoperative and postoperative cardiovascular stability than propofol. Respiratory profile is stable and comparable in both the agents.