Original Articles
Metri Basavaraj C.*1, Peerapur
Abstract
Methicillin-resistant Staphylococcus aureus (MRSA) is now considered to be a community, state, national and international problem. Patients and the public are increasingly seeing MRSA and rates of MRSA infections as indicators of the quality of patient care. The present study was done to compare the antimicrobial susceptibility profile of the hospital - and community -acquired Methicillin resistant Staphylococcus aureus. Various clinical samples like pus, urine, stool, sputum, blood and other body fluids of patients attending Shri B M Patil Medical College and Hospital were selected for study for a period of one years from June 2012 to June 2013. Samples which yielded Staphylococcus aureus were included in the study. S. aureus was identified by conventional techniques. Antimicrobial susceptibility testing of the isolates were performed by Kirby Bauer disc diffusion method. Detection of the MRSA were done by Oxacillin disc diffusion method. The present study shows that the prevalence of MRSA isolates were more among the elderly people. MRSA isolates were more frequent in male patients. Majority of the isolates were from surgery department. Resistance was more among HA-MRSA isolates when compared to CA-MSSA isolates The most effective agent against MRSA isolates was linezolid, followed by tetracycline and piperacillin/tazobactam. The most effective antimicrobial agent against MRSA isolates were linezolid, followed by tetracycline and piperacillin/tazobactam. Linezolid should be used as reserve drug in treating MRSA infections. Therefore we recommend the use of tetracycline or piperacillin/tazobactam for treating infections caused MRSA isolates.