Clinical Isolates Resistance to Commonly Used Antibiotics: A Concern in Healthcare Setting

Olise CC, Simon-Oke IA and

Abstract

Antibiotics resistance is a global issue, becoming more intensified because of the diminishing number of new antibiotics. Samples were collected aseptically from hospital surfaces with swab sticks. Isolated microorganisms from the samples collected were identified using standard microbiological methods. A total of 109 isolates were obtained Staphylococcus aureus (29), Staphylococcus epidermidis (13), Streptococcus spp. (16), Escherichia coli (8), Klebsiella pneumonia (7), Proteus spp (5), Enterobacter aerogenes (6), Bacillus cereus (10), Micrococcus leteus (6) and Pseudomonas aeruginosa (9). Gram negative bacterial isolated in the study shows multi-drug resistance to about four to five of the antibiotics tested. Most notably E. coli, Enterobacter aerogenes, Klebsiella pneumonia, and Proteus mirabilis. Although Tarivid and Perfloxacin demonstrated a high potency against these organisms. All Gram positive isolate shows 100% resistance to Ampiclox and Zannicef. Staphylococcus epidermidis, and Staphylococcus. aureus shows resistance to multiple antibiotics. The present of multidrug resistance microorganism in hospital environment is a concern in healthcare delivery.