C23-carbazole alkaloids from malayan Murraya koenigii (L.) spreng

Siow-Ping Tan, Mohd Azlan Nafi

Abstract

Murraya koenigii (Curry leaf tree), from the Rutaceae family, is a medicinally important herb of Indian origin and now were widely distributed throughout southern Asia. The bark of Malayan Murraya koenigii was selected for phytochemical investigation. The isolation of chemical constituents from its hexane and dichloromethane extract was carried out by using different chromatographic techniques. Six carbazoles with C23-framework was isolated and identified as mahanimbine, murrayamine-J, murrayazolinol, mahanimbilol, murrayakoeninol and bicyclomahanimbine. The structural characterization of the isolated compounds was supported by spectroscopic methods, including NMR, IR, UV, MS spectra data.

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