Selvaraj G, Kaliamurthi S
Abstract
Determination of biological metabolites is serious of analytical process to researchers in the field of biological sciences. In this context, the US Food and Drug Administration (FDA) published a draft of Guidance for Industry to the synthesis and produce bioactive substances and drugs. According to this guidance, before a drug can be legally marketed, its spectroscopic or chromatographic fingerprints and chemical assay of characteristic markers are required. Because of the complex nature of a typical drug and the lack of knowledge of its active constituent(s), the FDA may rely on a combination of tests and controls to ensure the identity, purity, quality, strength, potency, and consistency of natural bioactive compounds and drug-like candidates. It is well known, approximately the plants are a bio-synthesized wide range of around 2,00,000 metabolites. The chemical composition and biomedical potential of various coastal and traditional plants were reported.