Review Article
Bahareh Shayanrad, Seyyed Amir
Abstract
Breast cancer has been known as the most common cancer and the most common malignancy among women and also has been proven as the first cancer-related cause of death among them. Genetic diversity of several genes is related to breast cancer. Since this molecular approach is mainly limited to cell cycle genes, we intend to evaluate statistically the relation of the genes killer-cell immunoglobulin-like receptors (KIRs) as a systematic review. Through our re-analysis on the new hypothetical population made up of previous studies, we conclude that breast cancer is protected by KIR2DL1 and affected by KIR2DL2.