Bi(OTf)3 as a powerful and efficient catalyst for the synthesis of highly functionalized piperidines

Louisa Chouguiat, Raouf Boulci

Abstract

A simple, and efficient multicomponent synthesis of a highly functionalized piperidines has been developed based on a low-cost and environmentally benign Bi(OTf)3 catalyst via a one-pot condensation of aromatic aldehydes, β- ketoesters and aromatic amines