Antioxidant activity of extracts, cis and trans tilirosides, and other compounds from Thymelaea microphylla Coss. et Dur.

Research Article

Tarak Mekhelfi, Khawla Adouni,

Abstract

In the present study, we report the following: isolation and structural elucidation of two previously unknown in Thymelaea microphylla compounds, ethyl caffeate 1 and ladanein 2; evaluation of antioxidant properties and total phenolic content (TPC) of T. microphylla extracts; photoisomerization of cis/trans-tilirosides and structureantioxidant activity relationship of these two isomers. The petroleum ether and chloroform extracts were tested by DPPH•, ABTS •+ scavenging capacity (RSC) and ferric reducing antioxidant power (FRAP) assays. The results showed that there is a strong correlation between TPC and antioxidant activity of different T. microphylla extracts. Photoisomerization was induced by UV lamps at 365 nm, the percentage of cis-tiliroside was observed to increase up to 30%. Antioxidant activity was found to increase after phtoisomerization of tiliroside.

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