Antidiarrhoeal activity of methanolic extract of Justica procumbens by castoroil and enterpooling induced methods in rats

Research Article

K. Veeresh, V. Manasa, Vijusha

Abstract

Methanolic extract was prepared by using Leaves of Justica procumbens were tested for anti-diarrhoeal activity in different experimental animal models like castor oil induced, and Enterpooling test in rats. The toxicity values were established and 1/10th dose of the Methanolic extracts i.e. 300mg/kg and 500mg/kg were used for the entire study of anti diarrhoeal activities in rats. Antidiarrhoeal potential of extracts was evidenced by a significant reduction in faecal output in castor oil induced diarrhea and also a significant decrease in propulsive movement of gastrointestinal contents.

Relevant Publications in Der Pharmacia Lettre