Ioanna G. Alexandropoulou, The
Abstract
Legionella bacteria are the causative agent of legionellosis, an infection mainly acquired through aspiration of contaminated water. Macrolides and flouroquinolones are the treatment of choice for legionellosis. The selection of these categories is mainly based on clinical experience. Especially erythromycin was the first line drug in the treatment of legionellosis, even though erythomycin resistant strains can easily be obtained in vitro. Flouroquinolones has been shown to succeed high intracellular inhibition of Legionella compared with erythromycin