Adipocytokines as a risk factor for coronary artery disease and its relationships with Obesity

Mufeed J. Ewadh

Abstract

Obesity is a major health problem consistently increasing many severe complications such as metabolic syndrome, the risk for cardiovascular diseases, respiratory disorders and diabetic . Adipose tissue is an endocrine organ that manufacture actively biological structures defined as “adipocytokine”. Aims of the study are to Investigate the association of a set of adipocytokines ,including adiponectin, insulin and insulin resistant with CAD events in obsess patient. This study was included (88) males, There were 22 obese males and 22 normal weight males with CAD. 44 subjects who were an apparently healthy control group their ages between (45-65 years) in Babylon province / Iraq . The present study, observed, a significantly decrease in adiponectin in both CAD groups (obese and normal weight) when compared with control) groups and lower in obese when compared with control , while significant increase insulin and insulin resistant in both CAD groups (obese and normal weight) when compared with control groups and more elevation in obese groups.