A simple and reproducible crystallization method for the preparation of 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid (febuxostat) polymorphic form-B via acetic acid solvate

Chandra Kant Belwal and Kaushi

Abstract

A simple and reproducible crystallization method was developed for the synthesis of xanthine oxidase inhibitor febuxostat polymorphic form- B via acetic acid solvate.