A Review: Significance of topological tools as prognostic indicators in different etiologies.

Surampudi S

Abstract

Complexity is the mutual co-ordination between spatial orientation, dimensional adjustability, dynamical movement, synergistic activation and controls. The above said conditions are common in Human Biological systems. The existence and its property based dynamism studies are playing an important role to understand original existence and its alterations during health and disease. To study the topological features of these biological components of different systems by using mathematical constraints will be helpful to determine the prognostic indicators in Healthy population. One of the well known mathematical constraints (Geometrical constraint) is Phase Angle. It has wide applications in different fields of science like protein chemistry, membrane biology, Ion channel studies, molecular Biology and Nutrition (all interconnected areas). Phase Angle studies will be helpful to know the status or orientation of the bio molecules or functional units which has a wide functional network with other higher level of communicating systems. One of the key areas is to determine the Nutritional strengths of the cell membrane during the assessment of Body Composition.

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