A randomized, double-blind, comparative trial of nifedipine and methyldopa in moderate pregnancy induced hypertension

J. Aparna

Abstract

To assess the efficacy and safety of nifedipine compared with methyldopa in the management of moderate pregnancy induced hypertension (PIH). One hundred pregnant patients with moderate PIH were randomly allocated to receive either methyldopa or nifedipine. The dose of the drugs was doubled every 48 hours to maintain a mean systolic arterial blood pressure < 150 mmHg and mean diastolic blood pressure