Research Article
M. I. Fazal Mohamed1 , M. Seen
Abstract
Owing to the extensive pharmacological importance, heterocyclic compounds are often synthesized with varying substituents. The main objective of such synthesis is to study the activity related aspects of pharmacophore groups of the heterocyclic compounds and to enhance the yield of the compounds if found significantly active. Since spiro hetrocycles are expected to be pharmacologically active, compounds viz., N-[1-acetyl-7,9-diphenyl-4-oxa-8-thia-1,2-diazaspiro(4.5)dec-2-en-3-yl]acetamide and N-[1-acetyl-7,9-diphenyl-4,8-dithia-1,2-diazaspiro(4.5)dec-2-en-yl]acetamide have been synthesized and characterized by C,H,N anaylsis, IR, 1H-NMR and 13C-NMR data