A new method for the synthesis of juglone

Hong Li, Rui Liu, Yingchao Ji

Abstract

In the present study, an appropriate synthetic route was adopted to produce the target synthesis of Juglone. In the first of these objectives, 5-nitro-1,4-naphthoquinone had been synthesized by direct nitration of 1,4-naphthoquinone in the presence of water and sulfuric acid. Then the intermediate synthesis of 5-amino-1,4-naphthoquinone was obtained by the reduction of nitro. Finally, Juglone was produced after the hydrolysis of diazonium salt of 5-amino-1,4-naphthoquinone. The chemical structure of the product obtained by the process of the present study was verified by IR and 1H NMR. The data accord well with those recorded on literatures.