A New Mannich Base and its Metal Complexes along with their Antimicrobial and Antifungal screening

Mohd. Rais Khan and Sahdev

Abstract

A new Mannich base, N-(piperidino-1-yl-5-bromophenyl) benzamide, formed by the condensation of Piperadine, benzamide and 5-bromophenyl benzaldehyde and its Ti(III) V(III),VO(IV), Ru(II), Ru(III), MoO(V), MoO2(VI), UO2(VI), Co(III), and Mn(III) complexes haʋe been Synthesized. Their probable structures have been proposed on the basis of their microanalytical, IR, UV-vis. 1H NMR spectral data. All the complexes exhibit octahedral geometry. The biological activities of the ligand and its metal chelates against the bacteria E.coli, Staphylococcus aureus, Klebsiella pneumonia, Salmonella typhi, Pseudomonas aeruginosa and Shigella flexnri are also being reported.