Original Article
Chavakula R, Chakradhar Saladi
Abstract
An industrially viable synthesis of racemic 3-quinuclidinol under solvent free conditions, a key intermediate of 3-R-Quinuclidinol (R-1-azabicyclo[2,2,2]octan-3-ol) is used as a building block in the synthesis of muscarine M1 and M3 agonists as well as for muscarine M3 antagonists has been described.