Original Articles
M. Hari Krishna* and P. Thrive
Abstract
An expeditious and greener one-pot procedure was developed for the synthesis of 2-substituted-1H-perimidine derivatives. In the presence of catalytic amount of NBS, aldehydes and 1,8-diaminonaphthalene were converted into the corresponding 2-substituted-1H-perimidine derivatives in moderate to high yields under sonication. Highly efficient and simple methods have been described in this manuscript for the synthesis with competent yields. Present synthesis complies with principle of Green chemistry. As part of current studies, we here in report economical practical techniques like ultrasonic wave organic synthesis and by application of green solvents. On completion of reaction the products were characterized by IR, NMR and Mass Spectra. These methods are more convenient and reactions can be carried out in higher yield (94-97%), shorter reaction time (08mins-20mins) and milder conditions, without generation of pollution and safer to analyst.